Methotrexate-associated Intravascular Large B-cell Lymphoma in a Patient with Rheumatoid Arthritis
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چکیده
منابع مشابه
Intravascular Large B-cell Lymphoma: A Report of Two Cases
One of the rare variants of extranodal large B-cell lymphoma is intravascular large B-cell lymphoma (IVLBCL). Characteristics of IVLBCL include intraluminal selective proliferation of atypical lymphoid cells in small to medium-sized vessels. The etiologic of IVLBCL is unknown, but due to the growth pattern of this tumor, it is speculated that IVLBCL is caused by a defect in homing receptor of t...
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This report concerns a 62-year-old man with primary cutaneous diffuse large B-cell lymphoma (PCLBCL), leg type that developed during methotrexate (MTX) treatment for rheumatoid arthritis (RA). Several tumors were observed on the left lower leg. A histological analysis showed diffuse proliferation of large neoplastic B-cells that were immunophenotypically CD10-/MUM1+/BCL6-/BCL2+ and cytogenetica...
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Primary Hepatic Lymphoma (PHL) is rare and possibly associated with viral hepatitis and autoimmune diseases. Scleroderma could exceptionally be complicated by lymphoma. We describe PHL occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. CT scan, performed to work-up abdominal discomfort, constipation, and ...
متن کامل[Cutaneous lymphoma associated with methotrexate in a patient with rheumatoid arthritis].
La artritis reumatoide (AR) se asocia a un mayor riesgo del desarrollo de linfomas, de 1,9-6,7 veces mayor que la población general1. El metotrexato (MTX), es un fármaco antirreumático modificador de la enfermedad, usado en el tratamiento de la AR y de otras patologías reumáticas. Los efectos adversos graves poco frecuentes asociados al tratamiento con MTX, son la neumonitis intersticial, aplas...
متن کاملIntravascular Large B-Cell Lymphoma
Case Presentation. A 69-year-old Hispanic male, with a past history of diabetes and coronary disease, was admitted for fever, diarrhea, and confusion of 4 weeks duration. Physical examination showed a disoriented patient with multiple ecchymoses, possible ascites, and bilateral scrotal swelling. Hemoglobin was 6.7, prothrombin time (PT) 21.4 seconds with international normalized ratio 2.1, part...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2016
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.55.6943